CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival

Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Human Leukocyte Antigen (HLA) machinery of antigen presentation is still unclear. We present d...

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Detalles Bibliográficos
Autores principales: Zeiner, P. S., Zinke, J., Kowalewski, D. J., Bernatz, S., Tichy, J., Ronellenfitsch, M. W., Thorsen, F., Berger, A., Forster, M. T., Muller, A., Steinbach, J. P., Beschorner, R., Wischhusen, J., Kvasnicka, H. M., Plate, K. H., Stefanović, S., Weide, B., Mittelbronn, M., Harter, P. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831742/
https://www.ncbi.nlm.nih.gov/pubmed/29490700
http://dx.doi.org/10.1186/s40478-018-0521-5

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