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Control of Hedgehog Signalling by the Cilia-Regulated Proteasome

The Hedgehog signalling pathway is evolutionarily highly conserved and essential for embryonic development of invertebrates and vertebrates. Consequently, impaired Hedgehog signalling results in very severe human diseases, ranging from holoprosencephaly to Pallister-Hall syndrome. Due to this great...

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Detalles Bibliográficos
Autores principales: Gerhardt, Christoph, Wiegering, Antonia, Leu, Tristan, Rüther, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831775/
https://www.ncbi.nlm.nih.gov/pubmed/29615591
http://dx.doi.org/10.3390/jdb4030027