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Variance component analysis to assess protein quantification in biomarker validation: application to selected reaction monitoring-mass spectrometry
BACKGROUND: In the field of biomarker validation with mass spectrometry, controlling the technical variability is a critical issue. In selected reaction monitoring (SRM) measurements, this issue provides the opportunity of using variance component analysis to distinguish various sources of variabili...
Autores principales: | Klich, Amna, Mercier, Catherine, Gerfault, Laurent, Grangeat, Pierre, Beaulieu, Corinne, Degout-Charmette, Elodie, Fortin, Tanguy, Mahé, Pierre, Giovannelli, Jean-François, Charrier, Jean-Philippe, Giremus, Audrey, Maucort-Boulch, Delphine, Roy, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831836/ https://www.ncbi.nlm.nih.gov/pubmed/29490628 http://dx.doi.org/10.1186/s12859-018-2075-8 |
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