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Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is a clonal malignant disorder characterized by an uncontrolled proliferation of immature B or T lymphocytes. Extensive studies have suggested an involvement of angiogenesis signaling in ALL progression and resistance to treatment. Thus, targeting angio...

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Detalles Bibliográficos
Autores principales:	Deng, Manman, Zha, Jie, Jiang, Zhiwu, Jia, Xian, Shi, Yuanfei, Li, Peng, Chen, Xiao Lei, Fang, Zhihong, Du, Zhiqiang, Xu, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831852/ https://www.ncbi.nlm.nih.gov/pubmed/29490645 http://dx.doi.org/10.1186/s12967-018-1421-y

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