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Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer’s disease, whereas amyloid deposition does not

BACKGROUND: The underlying mechanism of brain glucose hypometabolism, an invariant neurodegenerative feature that tightly correlates with cognitive impairment and disease progression of Alzheimer’s disease (AD), remains elusive. METHODS: Positron emission tomography with 2-[(18)F]fluoro-2-deoxy-d-gl...

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Detalles Bibliográficos
Autores principales:	Sang, Shaoming, Pan, Xiaoli, Chen, Zhichun, Zeng, Fan, Pan, Shumei, Liu, Huimin, Jin, Lirong, Fei, Guoqiang, Wang, Changpeng, Ren, Shuhua, Jiao, Fangyang, Bao, Weiqi, Zhou, Weiyan, Guan, Yihui, Zhang, Yiqiu, Shi, Hongcheng, Wang, Yanjiang, Yu, Xiang, Wang, Yun, Zhong, Chunjiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831864/ https://www.ncbi.nlm.nih.gov/pubmed/29490669 http://dx.doi.org/10.1186/s13195-018-0354-2

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