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Are We Eating Our Way to Prostate Cancer—A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150

MicroRNAs (miRNAs) are well established epigenetic modifiers. There is a lot of work being done to identify the evolutionary transfer of miRNAs both at intra- and interspecific levels. In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnost...

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Detalles Bibliográficos
Autores principales: Vaidyanathan, Venkatesh, Krishnamoorthy, Vetrivhel, Karunasinghe, Nishi, Jabed, Anower, Pallati, Radha, Kao, Chi Hsiu-Juei, Wang, Alice, Marlow, Gareth, Ferguson, Lynnette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831905/
https://www.ncbi.nlm.nih.gov/pubmed/29657260
http://dx.doi.org/10.3390/ncrna2020002
Descripción
Sumario:MicroRNAs (miRNAs) are well established epigenetic modifiers. There is a lot of work being done to identify the evolutionary transfer of miRNAs both at intra- and interspecific levels. In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnostic biomarker for prostate cancer using theories of evolution, bio-accumulation, and interspecific transfer of miRNAs.