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4-Hydroxy-2-nonenal Alkylated and Peroxynitrite Nitrated Proteins Localize to the Fused Mitochondria in Malpighian Epithelial Cells of Type IV Collagen Drosophila Mutants

Background. Human type IV collagenopathy is associated with mutations within the COL4A1 and to a less extent the COL4A2 genes. The proteins encoded by these genes form heterotrimers and are the highest molar ratio components of the ubiquitous basement membrane. The clinical manifestations of the COL...

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Detalles Bibliográficos
Autores principales: Kiss, András A., Popovics, Nikoletta, Boldogkői, Zsolt, Csiszár, Katalin, Mink, Mátyás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832051/
https://www.ncbi.nlm.nih.gov/pubmed/29651426
http://dx.doi.org/10.1155/2018/3502401