B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade

Helminth infection is known for generating large amounts of poly-specific IgE. Here we demonstrate that innate-like B1 cells are responsible for this IgE production during infection with the nematode parasites Nippostrongylus brasiliensis and Heligmosomoides polygyrus bakeri. In vitro analysis of B1...

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Detalles Bibliográficos
Autores principales: Martin, Rebecca K., Damle, Sheela R., Valentine, Yolander A., Zellner, Matthew P., James, Briana N., Lownik, Joseph C., Luker, Andrea J., Davis, Elijah H., DeMeules, Martha M., Khandjian, Laura M., Finkelman, Fred D., Urban, Joseph F., Conrad, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832064/
https://www.ncbi.nlm.nih.gov/pubmed/29444434
http://dx.doi.org/10.1016/j.celrep.2018.01.048

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