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Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-κB Activation in Human Myeloid Leukemia THP-1 Cells

Tumors highly express active heat shock protein 90 (Hsp90), which is involved in tumor survival and progression. Enhanced Toll-like receptor (TLR) 5 expression and signaling were reported to be associated with acute myeloid leukemia. In the present study, we investigated the possible modulatory effe...

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Detalles Bibliográficos
Autores principales:	Na, Bon Hyang, Hoang, Thi Xoan, Kim, Jae Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832108/ https://www.ncbi.nlm.nih.gov/pubmed/29651431 http://dx.doi.org/10.1155/2018/4319369

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