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Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years
Reference intervals (RIs) of carotid intima media thickness (CIMT) from large healthy population are still lacking in Latin America. The aim of this study was to determine CIMT RIs in a cohort of 1012 healthy subjects from Argentina. We evaluated if RIs for males and females and for left and right c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832113/ https://www.ncbi.nlm.nih.gov/pubmed/29992052 http://dx.doi.org/10.1155/2018/8086714 |
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author | Diaz, Alejandro Bia, Daniel Zócalo, Yanina Manterola, Hugo Larrabide, Ignacio Lo Vercio, Lucas Del Fresno, Mariana Cabrera Fischer, Edmundo |
author_facet | Diaz, Alejandro Bia, Daniel Zócalo, Yanina Manterola, Hugo Larrabide, Ignacio Lo Vercio, Lucas Del Fresno, Mariana Cabrera Fischer, Edmundo |
author_sort | Diaz, Alejandro |
collection | PubMed |
description | Reference intervals (RIs) of carotid intima media thickness (CIMT) from large healthy population are still lacking in Latin America. The aim of this study was to determine CIMT RIs in a cohort of 1012 healthy subjects from Argentina. We evaluated if RIs for males and females and for left and right carotids were necessary. Second, mean and standard deviation (SD) age-related equations were obtained for left, right, and average (left + right)/2) CIMT using parametric regression methods based on fractional polynomials, in order to obtain age-specific percentiles curves. Age-specific percentile curves were obtained. Males showed higher A-CIMT (0.577 ± 0.003 mm versus 0.566 ± 0.004 mm, P = 0.039) in comparison with females. For males, the equations were as follows: A-CIMT mean = 0.42 + 8.14 × 10(−5)⁎Age(2); A-CIMT SD = 5.9 × 10(−2) + 1.09 × 10(−5)⁎Age(2). For females, they were as follows: A-CIMT mean = 0.40 + 8.20 × 10(−5)⁎Age(2); A-CIMT SD = 4.67 × 10(−2) + 1.63 × 10(−5)⁎Age(2). Our study provides the largest database concerning RIs of CIMT in healthy people in Argentina. Specific RIs and percentiles of CIMT for children, adolescents, and adults are now available according to age and gender, for right and left common carotid arteries. |
format | Online Article Text |
id | pubmed-5832113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58321132018-07-10 Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years Diaz, Alejandro Bia, Daniel Zócalo, Yanina Manterola, Hugo Larrabide, Ignacio Lo Vercio, Lucas Del Fresno, Mariana Cabrera Fischer, Edmundo Int J Hypertens Research Article Reference intervals (RIs) of carotid intima media thickness (CIMT) from large healthy population are still lacking in Latin America. The aim of this study was to determine CIMT RIs in a cohort of 1012 healthy subjects from Argentina. We evaluated if RIs for males and females and for left and right carotids were necessary. Second, mean and standard deviation (SD) age-related equations were obtained for left, right, and average (left + right)/2) CIMT using parametric regression methods based on fractional polynomials, in order to obtain age-specific percentiles curves. Age-specific percentile curves were obtained. Males showed higher A-CIMT (0.577 ± 0.003 mm versus 0.566 ± 0.004 mm, P = 0.039) in comparison with females. For males, the equations were as follows: A-CIMT mean = 0.42 + 8.14 × 10(−5)⁎Age(2); A-CIMT SD = 5.9 × 10(−2) + 1.09 × 10(−5)⁎Age(2). For females, they were as follows: A-CIMT mean = 0.40 + 8.20 × 10(−5)⁎Age(2); A-CIMT SD = 4.67 × 10(−2) + 1.63 × 10(−5)⁎Age(2). Our study provides the largest database concerning RIs of CIMT in healthy people in Argentina. Specific RIs and percentiles of CIMT for children, adolescents, and adults are now available according to age and gender, for right and left common carotid arteries. Hindawi 2018-02-14 /pmc/articles/PMC5832113/ /pubmed/29992052 http://dx.doi.org/10.1155/2018/8086714 Text en Copyright © 2018 Alejandro Diaz et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Diaz, Alejandro Bia, Daniel Zócalo, Yanina Manterola, Hugo Larrabide, Ignacio Lo Vercio, Lucas Del Fresno, Mariana Cabrera Fischer, Edmundo Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title | Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title_full | Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title_fullStr | Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title_full_unstemmed | Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title_short | Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11–81 Years |
title_sort | carotid intima media thickness reference intervals for a healthy argentinean population aged 11–81 years |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832113/ https://www.ncbi.nlm.nih.gov/pubmed/29992052 http://dx.doi.org/10.1155/2018/8086714 |
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