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Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats

OBJECTIVE: Special hypoxic and hypertonic microenvironment in intervertebral discs (IVDs) decreases the treatment effect of cell transplantation. We investigated the hypothesis that hypoxic preconditioning (HP) could improve the therapeutic effect of bone mesenchymal stem cells (BMSCs) to IVD degene...

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Detalles Bibliográficos
Autores principales:	Wang, Weiheng, Wang, Yang, Deng, Guoying, Ma, Jun, Huang, Xiaodong, Yu, Jiangming, Xi, Yanhai, Ye, Xiaojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832130/ https://www.ncbi.nlm.nih.gov/pubmed/29535780 http://dx.doi.org/10.1155/2018/7564159

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