Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome

Individuals with Down syndrome (DS) can develop Alzheimer's disease as early as 30 to 40 years old, but parkinsonism is rarely described. We report on a 20-year-old woman with Down syndrome and parkinsonism who responded dramatically to carbidopa-levodopa. We propose that the occurrence of park...

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Detalles Bibliográficos
Autores principales: Palat, Padmini, Hickey, Francis, Patel, Lina, Sannar, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832135/
https://www.ncbi.nlm.nih.gov/pubmed/29666730
http://dx.doi.org/10.1155/2018/2314791
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author Palat, Padmini
Hickey, Francis
Patel, Lina
Sannar, Elise
author_facet Palat, Padmini
Hickey, Francis
Patel, Lina
Sannar, Elise
author_sort Palat, Padmini
collection PubMed
description Individuals with Down syndrome (DS) can develop Alzheimer's disease as early as 30 to 40 years old, but parkinsonism is rarely described. We report on a 20-year-old woman with Down syndrome and parkinsonism who responded dramatically to carbidopa-levodopa. We propose that the occurrence of parkinsonism in individuals with DS may be underreported. Recognizing and treating this condition may improve quality of life.
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spelling pubmed-58321352018-04-17 Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome Palat, Padmini Hickey, Francis Patel, Lina Sannar, Elise Case Rep Neurol Med Case Report Individuals with Down syndrome (DS) can develop Alzheimer's disease as early as 30 to 40 years old, but parkinsonism is rarely described. We report on a 20-year-old woman with Down syndrome and parkinsonism who responded dramatically to carbidopa-levodopa. We propose that the occurrence of parkinsonism in individuals with DS may be underreported. Recognizing and treating this condition may improve quality of life. Hindawi 2018-02-15 /pmc/articles/PMC5832135/ /pubmed/29666730 http://dx.doi.org/10.1155/2018/2314791 Text en Copyright © 2018 Padmini Palat et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Palat, Padmini
Hickey, Francis
Patel, Lina
Sannar, Elise
Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title_full Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title_fullStr Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title_full_unstemmed Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title_short Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome
title_sort levodopa-responsive early-onset parkinsonism in down syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832135/
https://www.ncbi.nlm.nih.gov/pubmed/29666730
http://dx.doi.org/10.1155/2018/2314791
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AT sannarelise levodoparesponsiveearlyonsetparkinsonismindownsyndrome

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