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Statistical power and utility of meta-analysis methods for cross-phenotype genome-wide association studies

Advances in recent genome wide association studies (GWAS) suggest that pleiotropic effects on human complex traits are widespread. A number of classic and recent meta-analysis methods have been used to identify genetic loci with pleiotropic effects, but the overall performance of these methods is no...

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Detalles Bibliográficos
Autores principales:	Zhu, Zhaozhong, Anttila, Verneri, Smoller, Jordan W., Lee, Phil H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832233/ https://www.ncbi.nlm.nih.gov/pubmed/29494641 http://dx.doi.org/10.1371/journal.pone.0193256

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