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MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo
There is a high quest for novel therapeutic strategies to enhance recovery after stroke. MicroRNA-124 (miR-124) has been described as neuroprotective and anti-inflammatory molecule. Moreover, miR-124 is a well described enhancer of adult neurogenesis that could offer potentially beneficial effects....
Autores principales: | Saraiva, Cláudia, Talhada, Daniela, Rai, Akhilesh, Ferreira, Raquel, Ferreira, Lino, Bernardino, Liliana, Ruscher, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832317/ https://www.ncbi.nlm.nih.gov/pubmed/29494665 http://dx.doi.org/10.1371/journal.pone.0193609 |
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