A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products

Chromosomal instability and associated chromosomal aberrations are hallmarks of cancer and play a critical role in disease progression and development of resistance to drugs. Single-cell genome analysis has gained interest in latest years as a source of biomarkers for targeted-therapy selection and...

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Detalles Bibliográficos
Autores principales: Ferrarini, Alberto, Forcato, Claudio, Buson, Genny, Tononi, Paola, del Monaco, Valentina, Terracciano, Mario, Bolognesi, Chiara, Fontana, Francesca, Medoro, Gianni, Neves, Rui, Möhlendick, Birte, Rihawi, Karim, Ardizzoni, Andrea, Sumanasuriya, Semini, Flohr, Penny, Lambros, Maryou, de Bono, Johann, Stoecklein, Nikolas H., Manaresi, Nicolò
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832318/
https://www.ncbi.nlm.nih.gov/pubmed/29494651
http://dx.doi.org/10.1371/journal.pone.0193689

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