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An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat

Central nervous system (CNS) neurons fail to regrow injured axons, often resulting in permanently lost neurologic function. Tacrolimus is an FDA-approved immunosuppressive drug with known neuroprotective and neuroregenerative properties in the CNS. However, tacrolimus is typically administered syste...

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Detalles Bibliográficos
Autores principales:	van der Merwe, Yolandi, Faust, Anne E., Conner, Ian, Gu, Xinzhu, Feturi, Firuz, Zhao, Wenchen, Leonard, Bianca, Roy, Souvik, Gorantla, Vijay S., Venkataramanan, Raman, Washington, Kia M., Wagner, William R., Steketee, Michael B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832622/ https://www.ncbi.nlm.nih.gov/pubmed/29208469 http://dx.doi.org/10.1016/j.ebiom.2017.11.017

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