Loss of mRNA surveillance pathways results in widespread protein aggregation

Eukaryotic cells contain translation-associated mRNA surveillance pathways which prevent the production of potentially toxic proteins from aberrant mRNA translation events. We found that loss of mRNA surveillance pathways in mutants deficient in nonsense-mediated decay (NMD), no-go decay (NGD) and n...

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Detalles Bibliográficos
Autores principales: Jamar, Nur Hidayah, Kritsiligkou, Paraskevi, Grant, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832753/
https://www.ncbi.nlm.nih.gov/pubmed/29497115
http://dx.doi.org/10.1038/s41598-018-22183-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832753/
https://www.ncbi.nlm.nih.gov/pubmed/29497115
http://dx.doi.org/10.1038/s41598-018-22183-2

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