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Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer
CDK4/6 inhibition substantially improves progression-free survival (PFS) for women with advanced estrogen receptor-positive breast cancer, although there are no predictive biomarkers. Early changes in circulating tumor DNA (ctDNA) level may provide early response prediction, but the impact of tumor...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832789/ https://www.ncbi.nlm.nih.gov/pubmed/29497091 http://dx.doi.org/10.1038/s41467-018-03215-x |