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Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model

With the increasing prevalence of artemisinin-resistant malaria parasites, a highly efficacious and durable vaccine for malaria is urgently required. We have developed an experimental virus-vectored vaccine platform based on an envelope-modified baculovirus dual-expression system (emBDES). Here, we...

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Detalles Bibliográficos
Autores principales:	Yoshida, Kunitaka, Iyori, Mitsuhiro, Blagborough, Andrew M., Salman, Ahmed M., Dulal, Pawan, Sala, Katarzyna A., Yamamoto, Daisuke S., Khan, Shahid M., Janse, Chris J., Biswas, Sumi, Yoshii, Tatsuya, Yusuf, Yenni, Tokoro, Masaharu, Hill, Adrian V. S., Yoshida, Shigeto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832798/ https://www.ncbi.nlm.nih.gov/pubmed/29497047 http://dx.doi.org/10.1038/s41598-018-21369-y

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