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Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study
A recent pre-clinical study has shown that brain-penetrating statins can reduce risks of relapse to cocaine and nicotine addiction in rats. Based on this information, we conducted a randomized, double-blind, placebo-controlled, proof-of-concept trial to assess the efficacy of simvastatin in smoking...
Autores principales: | Ingrand, Isabelle, Solinas, Marcello, Ingrand, Pierre, Dugast, Emilie, Saulnier, Pierre-Jean, Pérault-Pochat, Marie-Christine, Lafay-Chebassier, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832803/ https://www.ncbi.nlm.nih.gov/pubmed/29497063 http://dx.doi.org/10.1038/s41598-018-21819-7 |
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