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Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase

Hepatocellular carcinoma (HCC) is one of the most aggressive malignant tumors, of which treatment options are limited especially in advanced stage. Bufalin, the major digoxin-like component of the traditional Chinese medicine Chansu, exhibits significant antitumor activities in hepatoma cells, but t...

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Detalles Bibliográficos
Autores principales: Yu, Zhuo, Feng, Hai, Sun, Xuehua, Zhuo, Yunhui, Li, Man, Zhou, Zhenhua, Huang, Lingying, Jiang, Yun, Zhu, Xiaojun, Zhang, Xin, Le, Fan, Zheng, Chao, Cheng, Alfred Szelok, Gao, Yueqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832857/
https://www.ncbi.nlm.nih.gov/pubmed/29497076
http://dx.doi.org/10.1038/s41598-018-22113-2