Conditional knockout of Na(V)1.6 in adult mice ameliorates neuropathic pain

Voltage-gated sodium channels Na(V)1.7, Na(V)1.8 and Na(V)1.9 have been the focus for pain studies because their mutations are associated with human pain disorders, but the role of Na(V)1.6 in pain is less understood. In this study, we selectively knocked out Na(V)1.6 in dorsal root ganglion (DRG) n...

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Detalles Bibliográficos
Autores principales: Chen, Lubin, Huang, Jianying, Zhao, Peng, Persson, Anna-Karin, Dib-Hajj, Fadia B., Cheng, Xiaoyang, Tan, Andrew, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832877/
https://www.ncbi.nlm.nih.gov/pubmed/29497094
http://dx.doi.org/10.1038/s41598-018-22216-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832877/
https://www.ncbi.nlm.nih.gov/pubmed/29497094
http://dx.doi.org/10.1038/s41598-018-22216-w

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