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Conditional knockout of Na(V)1.6 in adult mice ameliorates neuropathic pain
Voltage-gated sodium channels Na(V)1.7, Na(V)1.8 and Na(V)1.9 have been the focus for pain studies because their mutations are associated with human pain disorders, but the role of Na(V)1.6 in pain is less understood. In this study, we selectively knocked out Na(V)1.6 in dorsal root ganglion (DRG) n...
Autores principales: | Chen, Lubin, Huang, Jianying, Zhao, Peng, Persson, Anna-Karin, Dib-Hajj, Fadia B., Cheng, Xiaoyang, Tan, Andrew, Waxman, Stephen G., Dib-Hajj, Sulayman D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832877/ https://www.ncbi.nlm.nih.gov/pubmed/29497094 http://dx.doi.org/10.1038/s41598-018-22216-w |
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