Cargando…

Histone methylation regulates Hif‐1 signaling cascade in activation of hepatic stellate cells

Liver fibrosis is characterized by deposition of excessive extracellular matrix (ECM). The major source of ECM is activated hepatic stellate cells (HSCs). Previously, we reported that hypoxia‐inducible factor‐1 (Hif‐1) regulates activation of HSCs through autophagy. In current work, human HSC cell l...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Fei, Wan, Lu, Liu, Jie, Huang, Ke, Xiao, Zhenmeng, Zhang, Yingjing, Shi, Chunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832973/
https://www.ncbi.nlm.nih.gov/pubmed/29511617
http://dx.doi.org/10.1002/2211-5463.12379