The combined effect of Pdx1 overexpression and Shh manipulation on the function of insulin‐producing cells derived from adipose‐tissue stem cells

Pancreatic and duodenal homeobox 1 (Pdx1) and Sonic hedgehog (Shh) are the key regulators of beta‐cell function. In vitro experiments have shown that there is significant cooperation between Pdx1 and Shh with regard to the production and maintenance of insulin‐producing cells (IPCs). In this study,...

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Detalles Bibliográficos
Autores principales: Hashemi Tabar, Mahmoud, Tabandeh, Mohammad Reza, Moghimipour, Eskandar, Dayer, Dian, Ghadiri, Ata A., Allah Bakhshi, Elham, Orazizadeh, Mahmoud, Ghafari, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832980/
https://www.ncbi.nlm.nih.gov/pubmed/29511614
http://dx.doi.org/10.1002/2211-5463.12378

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