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p62/SQSTM1 promotes rapid ubiquitin conjugation to target proteins after endosome rupture during xenophagy

Autophagy is a bulk degradation pathway, and selective autophagy to remove foreign entities is called xenophagy. The conjugation of ubiquitin to target pathogens is an important process in xenophagy but when and where this ubiquitination occurs remains unclear. Here, we analyzed the temporal sequenc...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Megumi, Ogawa, Hidesato, Koujin, Takako, Mori, Chie, Osakada, Hiroko, Kobayashi, Shouhei, Hiraoka, Yasushi, Haraguchi, Tokuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832981/
https://www.ncbi.nlm.nih.gov/pubmed/29511624
http://dx.doi.org/10.1002/2211-5463.12385

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