Cargando…

PEGylation and Dimerization of Expressed Proteins under Near Equimolar Conditions with Potassium 2-Pyridyl Acyltrifluoroborates

[Image: see text] The covalent conjugation of large, functionalized molecules remains a frontier in synthetic chemistry, as it requires rapid, chemoselective reactions. The potassium acyltrifluoroborate (KAT)–hydroxylamine amide-forming ligation shows promise for conjugations of biomolecules under a...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Christopher J., Bode, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833003/
https://www.ncbi.nlm.nih.gov/pubmed/29532019
http://dx.doi.org/10.1021/acscentsci.7b00432