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17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms

BACKGROUND: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by two core symptoms: impaired social interaction and communication, and restricted, repetitive behaviors and interests. The pathophysiology of ASD is not yet fully understood, due to a plethora of ge...

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Detalles Bibliográficos
Autores principales: Filice, Federica, Lauber, Emanuel, Vörckel, Karl Jakob, Wöhr, Markus, Schwaller, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833085/
https://www.ncbi.nlm.nih.gov/pubmed/29507711
http://dx.doi.org/10.1186/s13229-018-0199-3