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A new cell culture model to genetically dissect the complete human papillomavirus life cycle

Herein, we describe a novel infection model that achieves highly efficient infection of primary keratinocytes with human papillomavirus type 16 (HPV16). This cell culture model does not depend on immortalization and is amenable to extensive genetic analyses. In monolayer cell culture, the early but...

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Detalles Bibliográficos
Autores principales: Bienkowska-Haba, Malgorzata, Luszczek, Wioleta, Myers, Julia E., Keiffer, Timothy R., DiGiuseppe, Stephen, Polk, Paula, Bodily, Jason M., Scott, Rona S., Sapp, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833277/
https://www.ncbi.nlm.nih.gov/pubmed/29494681
http://dx.doi.org/10.1371/journal.ppat.1006846