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Wolbachia-mediated virus blocking in mosquito cells is dependent on XRN1-mediated viral RNA degradation and influenced by viral replication rate
Wolbachia is currently being developed as a novel tool to block the transmission of dengue viruses (DENV) by Aedes aegypti. A number of mechanisms have been proposed to explain the DENV-blocking phenotype in mosquitoes, including competition for fatty acids like cholesterol, manipulation of host miR...
Autores principales: | Thomas, Saijo, Verma, Jiyoti, Woolfit, Megan, O’Neill, Scott L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833283/ https://www.ncbi.nlm.nih.gov/pubmed/29494679 http://dx.doi.org/10.1371/journal.ppat.1006879 |
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