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Wolbachia-mediated virus blocking in mosquito cells is dependent on XRN1-mediated viral RNA degradation and influenced by viral replication rate

Wolbachia is currently being developed as a novel tool to block the transmission of dengue viruses (DENV) by Aedes aegypti. A number of mechanisms have been proposed to explain the DENV-blocking phenotype in mosquitoes, including competition for fatty acids like cholesterol, manipulation of host miR...

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Detalles Bibliográficos
Autores principales: Thomas, Saijo, Verma, Jiyoti, Woolfit, Megan, O’Neill, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833283/
https://www.ncbi.nlm.nih.gov/pubmed/29494679
http://dx.doi.org/10.1371/journal.ppat.1006879

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