Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat

Treatments for osteoarthritis (OA) are designed to restore chondrocyte function and inhibit cell apoptosis. Previous studies have shown that activation of the glucagon-like peptide-1 receptor (GLP-1R) leads to anti-inflammatory and anti-apoptotic effects. However, the role of GLP-1R in the pathologi...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Xie, Jun-Jun, Shi, Ke-Si, Gu, Yun-Tao, Wu, Cong-Cong, Xuan, Jun, Ren, Yue, Chen, Long, Wu, Yao-Sen, Zhang, Xiao-Lei, Xiao, Jian, Wang, De-Zhong, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833344/
https://www.ncbi.nlm.nih.gov/pubmed/29434185
http://dx.doi.org/10.1038/s41419-017-0217-y

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