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Glycolysis promotes caspase-3 activation in lipid rafts in T cells
Resting T cells undergo a rapid metabolic shift to glycolysis upon activation in the presence of interleukin (IL)-2, in contrast to oxidative mitochondrial respiration with IL-15. Paralleling these different metabolic states are striking differences in susceptibility to restimulation-induced cell de...
Autores principales: | Secinaro, Michael A., Fortner, Karen A., Dienz, Oliver, Logan, Angela, Murphy, Michael P., Anathy, Vikas, Boyson, Jonathan E., Budd, Ralph C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833351/ https://www.ncbi.nlm.nih.gov/pubmed/29352186 http://dx.doi.org/10.1038/s41419-017-0099-z |
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