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Overexpression of parkin protects retinal ganglion cells in experimental glaucoma

Glaucoma is a leading cause of irreversible blindness and characterized by progressive damage of retinal ganglion cells (RGCs). Growing evidences have linked impaired mitophagy with neurodegenerative diseases, while the E3 ubiquitin ligase parkin may play a key role. However, the pathophysiological...

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Detalles Bibliográficos
Autores principales: Dai, Yi, Hu, Xinxin, Sun, Xinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833378/
https://www.ncbi.nlm.nih.gov/pubmed/29367744
http://dx.doi.org/10.1038/s41419-017-0146-9

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