EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

The epidermal growth factor receptor (EGFR) pathway and Hippo signaling play an important role in the carcinogenesis of hepatocellular carcinoma (HCC). However, the crosstalk between these two pathways and its implications in targeted therapy remains unclear. We found that the activated EGFR signali...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Hongwei, Dai, Xinyu, Yu, Huangfei, Zhou, Sheng, Fan, Zhenghai, Wei, Guoqing, Tang, Qiulin, Gong, Qiyong, Bi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833379/
https://www.ncbi.nlm.nih.gov/pubmed/29449645
http://dx.doi.org/10.1038/s41419-018-0302-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833379/
https://www.ncbi.nlm.nih.gov/pubmed/29449645
http://dx.doi.org/10.1038/s41419-018-0302-x

Ejemplares similares