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KRAS induces lung tumorigenesis through microRNAs modulation
Oncogenic KRAS induces tumor onset and development by modulating gene expression via different molecular mechanisms. MicroRNAs (miRNAs) are small non-coding RNAs that have been established as main players in tumorigenesis. By overexpressing wild type or mutant KRAS (KRAS(G12D)) and using inducible h...
Autores principales: | Shi, Lei, Middleton, Justin, Jeon, Young-Jun, Magee, Peter, Veneziano, Dario, Laganà, Alessandro, Leong, Hui-Sun, Sahoo, Sudhakar, Fassan, Matteo, Booton, Richard, Shah, Rajesh, Crosbie, Philip A. J., Garofalo, Michela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833396/ https://www.ncbi.nlm.nih.gov/pubmed/29440633 http://dx.doi.org/10.1038/s41419-017-0243-9 |
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