Long non-coding RNA and microRNA-675/let-7a mediates the protective effect of melatonin against early brain injury after subarachnoid hemorrhage via targeting TP53 and neural growth factor

The objective of this study was to identify the protective effect of melatonin (MT) against early brain injury (EBI) following subarachnoid hemorrhage (SAH) and explore the underlying molecular mechanism. Real-time polymerase chain reaction (PCR) and luciferase assay were utilized to detect the effe...

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Detalles Bibliográficos
Autores principales: Yang, Song, Tang, Wanzhong, He, Yuchao, Wen, Linbao, Sun, Bin, Li, Shengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833397/
https://www.ncbi.nlm.nih.gov/pubmed/29367587
http://dx.doi.org/10.1038/s41419-017-0155-8

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