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c-FLIP is a target of the E3 ligase deltex1 in gastric cancer

The ubiquitin E3 ligase DELTEX1 (DTX1) is specifically downregulated in gastric cancer tissues, and expression of DTX1 is linked to better prognoses and survival in gastric cancer. Cellular FLICE inhibitory protein (c-FLIP) is known for its pivotal role in the resistance of cancer cells to death rec...

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Detalles Bibliográficos
Autores principales: Hsu, Tzu-Sheng, Mo, Shu-Ting, Hsu, Ping-Ning, Lai, Ming-Zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833402/
https://www.ncbi.nlm.nih.gov/pubmed/29374180
http://dx.doi.org/10.1038/s41419-017-0165-6