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miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2

Treatment of lung cancer is an unmet need as it accounts for the majority of cancer deaths worldwide. The development of new therapies urges the identification of potential targets. MicroRNAs’ expression is often deregulated in cancer and their modulation has been proposed as a successful strategy t...

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Detalles Bibliográficos
Autores principales: Fiori, Micol E., Villanova, Lidia, Barbini, Chiara, De Angelis, Maria Laura, De Maria, Ruggero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833438/
https://www.ncbi.nlm.nih.gov/pubmed/29352138
http://dx.doi.org/10.1038/s41419-017-0080-x