Targeting deubiquitinase USP28 for cancer therapy

As one of the most important post-translational modifications, ubiquitination plays versatile roles in cancer-related pathways, and is involved in protein metabolism, cell-cycle progression, apoptosis, and transcription. Counteracting the activities of the E3 ligases, the deubiquitylating enzymes ha...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Liu, Zhiyi, Zhang, Li, Yang, Zhaozhi, Chen, Xingxing, Luo, Jurui, Zhou, Zhirui, Mei, Xin, Yu, Xiaoli, Shao, Zhimin, Feng, Yan, Fu, Shen, Zhang, Zhen, Wei, Dongping, Jia, Lijun, Ma, Jinli, Guo, Xiaomao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833459/
https://www.ncbi.nlm.nih.gov/pubmed/29415985
http://dx.doi.org/10.1038/s41419-017-0208-z

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