Atm reactivation reverses ataxia telangiectasia phenotypes in vivo

Hereditary deficiencies in DNA damage signaling are invariably associated with cancer predisposition, immunodeficiency, radiation sensitivity, gonadal abnormalities, premature aging, and tissue degeneration. ATM kinase has been established as a central player in DNA double-strand break repair and it...

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Detalles Bibliográficos
Autores principales: Di Siena, Sara, Campolo, Federica, Gimmelli, Roberto, Di Pietro, Chiara, Marazziti, Daniela, Dolci, Susanna, Lenzi, Andrea, Nussenzweig, Andre, Pellegrini, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833483/
https://www.ncbi.nlm.nih.gov/pubmed/29472706
http://dx.doi.org/10.1038/s41419-018-0357-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833483/
https://www.ncbi.nlm.nih.gov/pubmed/29472706
http://dx.doi.org/10.1038/s41419-018-0357-8

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