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Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer

Sterol regulatory element-binding proteins (SREBPs) belong to a family of transcription factors that regulate the expression of genes required for the synthesis of fatty acids and cholesterol. Three SREBP isoforms, SREBP1a, SREBP1c, and SREBP2, have been identified in mammalian cells. SREBP1a and SR...

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Detalles Bibliográficos
Autores principales:	Wen, Yang-An, Xiong, Xiaopeng, Zaytseva, Yekaterina Y., Napier, Dana L., Vallee, Emma, Li, Austin T., Wang, Chi, Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833501/ https://www.ncbi.nlm.nih.gov/pubmed/29449559 http://dx.doi.org/10.1038/s41419-018-0330-6

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