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Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy

Premature senescence is a key process in the progression of diabetic nephropathy (DN). Premature senescence of renal tubular epithelial cells (RTEC) in DN may result from the accumulation of damaged mitochondria. Mitophagy is the principal process that eliminates damaged mitochondria through PTEN-in...

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Detalles Bibliográficos
Autores principales:	Chen, Kehong, Dai, Huanzi, Yuan, Junjie, Chen, Jia, Lin, Lirong, Zhang, Weiwei, Wang, Limin, Zhang, Jianguo, Li, Kailong, He, Yani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833650/ https://www.ncbi.nlm.nih.gov/pubmed/29367621 http://dx.doi.org/10.1038/s41419-017-0127-z

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