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BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis
Small molecules targeting bromodomains of BET proteins possess strong anti-tumor activities and have emerged as potential therapeutics for cancer. However, the underlying mechanisms for the anti-proliferative activity of these inhibitors are still not fully characterized. In this study, we demonstra...
Autores principales: | Dong, Xingchen, Hu, Xiangming, Chen, Jinjing, Hu, Dan, Chen, Lin-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833665/ https://www.ncbi.nlm.nih.gov/pubmed/29434197 http://dx.doi.org/10.1038/s41419-017-0181-6 |
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