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BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis
Small molecules targeting bromodomains of BET proteins possess strong anti-tumor activities and have emerged as potential therapeutics for cancer. However, the underlying mechanisms for the anti-proliferative activity of these inhibitors are still not fully characterized. In this study, we demonstra...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833665/ https://www.ncbi.nlm.nih.gov/pubmed/29434197 http://dx.doi.org/10.1038/s41419-017-0181-6 |