CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing

The necroptotic cell death pathway is a key component of human pathogen defense that can become aberrantly derepressed during tissue homeostasis to contribute to multiple types of tissue damage and disease. While formation of the necrosome kinase signaling complex containing RIPK1, RIPK3, and MLKL h...

Descripción completa

Detalles Bibliográficos
Autores principales: Callow, Marinella G., Watanabe, Colin, Wickliffe, Katherine E., Bainer, Russell, Kummerfield, Sarah, Weng, Julie, Cuellar, Trinna, Janakiraman, Vasantharajan, Chen, Honglin, Chih, Ben, Liang, Yuxin, Haley, Benjamin, Newton, Kim, Costa, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833675/
https://www.ncbi.nlm.nih.gov/pubmed/29449584
http://dx.doi.org/10.1038/s41419-018-0301-y

Ejemplares similares

Ejemplares similares