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Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Pyruvate kinase M2 (PKM2) is a glycolytic enzyme that is expressed in cancer cells. Its role in tumor metabolism is not definitively established, but investigators have suggested that regulation of PKM2 activity can cause accumulation of glycolytic intermediates and increase flux through the pentose...

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Detalles Bibliográficos
Autores principales:	Rajala, Ammaji, Wang, Yuhong, Brush, Richard S., Tsantilas, Kristine, Jankowski, Connor S. R., Lindsay, Ken J., Linton, Jonathan D., Hurley, James B., Anderson, Robert E., Rajala, Raju V. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833680/ https://www.ncbi.nlm.nih.gov/pubmed/29445082 http://dx.doi.org/10.1038/s41419-018-0296-4

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