Cargando…
Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA
Recent studies show substantial growth-promoting properties of nicotine (NIC) in cancer, which is a combined outcome of genetic and epigenetic alterations. However, the role of epigenetic modifiers in response to NIC in breast cancer is less studied. In the present study, for the first time we have...
Autores principales: | Kumari, Kanchan, Das, Biswajit, Adhya, Amit, Chaudhary, Sanjib, Senapati, Shantibhusan, Mishra, Sandip K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833686/ https://www.ncbi.nlm.nih.gov/pubmed/29396474 http://dx.doi.org/10.1038/s41419-017-0224-z |
Ejemplares similares
-
Genome-wide expression analysis reveals six contravened targets of EZH2 associated with breast cancer patient survival
por: Kumari, Kanchan, et al.
Publicado: (2019) -
Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma
por: Kumari, Kanchan, et al.
Publicado: (2018) -
3-Deazaneplanocin A (DZNep), an Inhibitor of the Histone Methyltransferase EZH2, Induces Apoptosis and Reduces Cell Migration in Chondrosarcoma Cells
por: Girard, Nicolas, et al.
Publicado: (2014) -
DZNep, an inhibitor of the histone methyltransferase EZH2, suppresses hepatic fibrosis through regulating miR-199a-5p/SOCS7 pathway
por: Ding, Rongrong, et al.
Publicado: (2021) -
3-Deazaneplanocin A (DZNep), an Inhibitor of S-Adenosylmethionine-dependent Methyltransferase, Promotes Erythroid Differentiation
por: Fujiwara, Tohru, et al.
Publicado: (2014)