Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth

HSP60 is a mitochondrial localized quality control protein responsible for maintaining mitochondrial function. Although HSP60 is considered both a tumor suppressor and promoter in different types of cancer, the role of HSP60 in human pancreatic ductal adenocarcinoma (PDAC) remains unknown. In this s...

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Detalles Bibliográficos
Autores principales: Zhou, Chao, Sun, Hongwei, Zheng, Chen, Gao, Jing, Fu, Qingzi, Hu, Nianqi, Shao, Xiaoli, Zhou, Yingying, Xiong, Jingting, Nie, Ke, Zhou, Huaibin, Shen, Lijun, Fang, Hezhi, Lyu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833694/
https://www.ncbi.nlm.nih.gov/pubmed/29415987
http://dx.doi.org/10.1038/s41419-017-0196-z

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