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Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells

The damage-associated molecular pattern molecules (DAMPs) released by necrotic cells can trigger inflammatory response, which will facilitate the clearance of these dead cells. Neutrophil mobilization is a very important step for the dead cell clearance, however the detailed mechanisms for DAMPs ind...

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Detalles Bibliográficos
Autores principales: Su, Li, Li, Na, Tang, Hua, Lou, Ziyang, Chong, Xiaodan, Zhang, Chenxi, Su, Jiacan, Dong, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833701/
https://www.ncbi.nlm.nih.gov/pubmed/29476069
http://dx.doi.org/10.1038/s41419-018-0377-4