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Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination

Ubiquitin-specific protease 4 (USP4) is a member of the deubiquitinating enzyme family, which plays an important role in human tumor diseases. However, the mechanisms by which USP4 facilitates tumor development, especially in hepatocellular carcinoma (HCC), remain unclear. Clinically, we found that...

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Detalles Bibliográficos
Autores principales: Li, Tianyi, Yan, Bin, Ma, Yang, Weng, Junyong, Yang, Shouwen, Zhao, Nan, Wang, Xiaoliang, Sun, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833721/
https://www.ncbi.nlm.nih.gov/pubmed/29396555
http://dx.doi.org/10.1038/s41419-017-0182-5

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