The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer

Paclitaxel is widely used as a first-line chemotherapeutic drug for patients with ovarian cancer and other solid cancers, but drug resistance occurs frequently, resulting in ovarian cancer still presenting as the highest lethality among all gynecological tumors. Here, using DIGE quantitative proteom...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Feng, Yan, Wang, Xin-Yu, Zhang, Ya-Nan, Yuan, Chun-Nv, Zhang, Song-Fa, Shen, Yuan-Ming, Fu, Yun-Feng, Zhou, Cai-Yun, Li, Xiao, Cheng, Xiao-Dong, Lu, Wei-Guo, Xie, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833742/
https://www.ncbi.nlm.nih.gov/pubmed/29367628
http://dx.doi.org/10.1038/s41419-017-0137-x

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